Nui nā lāʻau lapaʻau i hiki ke hāʻawi ʻia ma ke ʻano he lāʻau lapaʻau waha (ma ka waha) no ka lymphoma a me ka leukemia lymphocytic mau loa.
Ka nānā ʻana o nā lāʻau lapaʻau waha ma lymphoma (& CLL)
ʻO ka lymphoma a me ka lymphocytic lymphoma maʻi (CLL) hiki ke hui pū ʻia me nā lāʻau anti-cancer. Hāʻawi pinepine ʻia lākou i loko o ke aʻa (intravenously) a hoʻokomo pinepine ʻia i ka hui pū ʻana o nā lāʻau lapaʻau me ka antibody therapy a me ka chemotherapy (immunochemotherapy).
Hoʻopili pinepine kēia i ka lawelawe ʻana i ka lāʻau lapaʻau ma kahi haukapila a i ʻole ma kahi kikowaena maʻi maʻi kūikawā. Eia nō naʻe, ua nui nā hanana o ka maʻi kanesa no ka mālama ʻana i ka lymphoma a me CLL i hiki ke lawe ʻia e ka waha ma ke ʻano papa. Ua kapa ʻia kēia mau lāʻau lapaʻau waha.
He aha nā lāʻau lapaʻau waha?
Hiki i nā lāʻau lapaʻau lymphoma waha ke lilo i nā lāʻau lapaʻau chemotherapy, nā lāʻau lapaʻau i kuhikuhi ʻia, a me nā immunotherapies. Hiki ke lawe ʻia e ka waha ma ke ʻano he papa, capsule, a i ʻole he wai. Hoʻopili ʻia ka lāʻau i loko o ke kahe koko a lawe ʻia e like me nā lāʻau lapaʻau intravenous.
Hiki i nā lāʻau lapaʻau waha ke ʻano like me nā koho intravenous a loaʻa iā lākou kekahi mau hopena ʻaoʻao ʻē aʻe. Nui nā kumu e pili ana i ka subtype o lymphoma a me ke kūlana olakino o ka mea maʻi e pono ke kaulike e koho i ka mālama maikaʻi loa o ka lymphoma. No laila,ʻoi aku ka maikaʻi o ka kohoʻana ma ke kūkākūkāʻana me ke kauka.
I ka manawa hea e hoʻohana ʻia ai nā lāʻau lapaʻau waha?
ʻO ka hapa nui o nā lāʻau lapaʻau waha i hoʻohana ʻia no ka mālama ʻana i ka lymphoma a me ka CLL he mau immunotherapy a i ʻole nā mea lapaʻau i hoʻopaʻa ʻia. Hoʻokumu ʻia nā lāʻau lapaʻau i hoʻopaʻa ʻia e kūʻē i nā enzyme kikoʻī e pono ai no ka ulu ʻana o ka lymphoma a ʻo nā lāʻau lapaʻau chemotherapy maʻamau ke kuhikuhi ʻia e kūʻē i ka puʻunaue wikiwiki ʻana inā he lymphoma lākou a i ʻole nā pūnaewele maʻamau i loko o ke kino kanaka.
No ka mea, ʻaʻole ʻokoʻa nā lāʻau lapaʻau chemotherapy ma waena o nā cell lymphoma a me nā cell olakino maʻamau, ua hōʻino lākou i nā cell olakino maʻamau e alakaʻi ana i nā hopena ʻaoʻao e like me ka emi ʻana o ke koko, ka lauoho lauoho, nā ʻeha waha, nausea, ka luaʻi a me ka maʻi maʻi maʻamau aʻo nā lāʻau lapaʻau i hoʻopaʻa ʻia e hoʻopilikia pinepine i ka liʻiliʻi o nā cell olakino maʻamau. i ka liʻiliʻi o kēia mau ʻano hopena koʻikoʻi.
Hoʻomaka i ka lāʻau lapaʻau waha
Ma mua o ka hoʻomaka ʻana o ka mālama ʻana ma ka home:
- Na ke kauka e kuhikuhi i ka lāʻau
- Na ke kauka lāʻau lapaʻau e hāʻawi i ka lāʻau no ka mea maʻi
- Hoʻonohonoho ʻia kahi manawa e kūkākūkā ai i ka mālama ʻana a me nā hopena ʻaoʻao e hiki mai ana
Na ke kahu a i ʻole ka lāʻau lapaʻau e wehewehe kikoʻī i ke ʻano o ka lawe ʻana i nā lāʻau lapaʻau a e hoʻokomo ʻia kēia i ke ʻano a me ka nui o ka lawe ʻana. E hāʻawi ʻia nā ʻōlelo aʻoaʻo no ka mālama pono ʻana a me ka mālama ʻana i nā lāʻau lapaʻau. E kūkākūkā ʻia nā hopena ʻaoʻao a pau o ka mālama ʻana, a e hāʻawi ʻia ka ʻike i kākau ʻia i ka mea maʻi.
Nā mea e ʻike e pili ana i ka lawe ʻana i nā lāʻau lapaʻau waha
Hiki i nā lāʻau lapaʻau waha ke lilo i koho kūpono no nā poʻe maʻi no ka mea hiki ke lawe ʻia ma ka home, akā naʻe aia kekahi mau mea e noʻonoʻo ai:
- No nā maʻi ke kuleana e hōʻoia i ka lawe ʻana i kā lākou lāʻau lapaʻau, no laila e piʻi aʻe paha ka pilikia o nā hewa lāʻau e like me ka poina ʻana i ka lāʻau lapaʻau.
i kekahi mau lā a i ʻole ka lawe ʻana i ka maʻi kūpono ʻole e hiki ke hoʻololi i ka pono o ka lāʻau. - He mea koʻikoʻi ka lawe ʻana o nā maʻi i nā lāʻau lapaʻau a pau e like me ka mea i kuhikuhi ʻia e hoʻonui i ka maikaʻi o ka mālama ʻana a e hōʻemi i nā hopena ʻaoʻao. Ma muli o ka paʻakikī o ka mālama ʻana i nā lāʻau lapaʻau āpau, e kamaʻilio me ka hui loea e pili ana i ka mālama ʻana i ke ala. Hiki ke kōkua ʻia nā ʻano mea hana like ʻole me ka hoʻopaʻa ʻana i ka lāʻau lapaʻau ma ka diary a i ʻole ka hana ʻana i nā hoʻomanaʻo pūnaewele ma nā polokalamu a i ʻole ma ke kelepona
- Hiki paha i ka poʻe maʻi ke hoʻohaʻahaʻa i ka pili ʻana i kā lākou hui loea ma mua o ka loaʻa ʻana o nā lāʻau lapaʻau intravenous no ka mea ʻaʻole pinepine lākou e kipa aku i ka haukapila a i ʻole ke kikowaena maʻi kanesa. Eia nō naʻe, ʻo ka lawe ʻana i nā lāʻau lapaʻau waha ma ka home he mea maikaʻi paha ia no nā poʻe maʻi e hele lōʻihi i ko lākou haukapila e pili ana i ka manawa a me ke kālā i hoʻolilo ʻia ma ka huakaʻi.
- Hiki ke ʻike ʻole ʻia nā hopena ʻaoʻao a ʻaʻole i hōʻike ʻia i ka hui loea a ʻaʻole maopopo i nā patent pehea e mālama ai i nā hopena ʻaoʻao ma ka home. No laila, he mea nui ka hoʻonaʻauao ʻana i nā mea maʻi a me nā mea mālama i kēia mau wahi koʻikoʻi. Hiki ke hoʻohaʻahaʻa ʻia ka nui o nā hopena ʻaoʻao o nā lāʻau lapaʻau waha e ka mālama kākoʻo no laila e nānā pono nā poʻe maʻi i nā hopena ʻaoʻao a pau o kā lākou mālama ʻana a hōʻike iā lākou i ka hui loea i ka wā e loaʻa ai, no laila e loaʻa iā lākou ka mālama maikaʻi loa.
ʻO ka mālama ʻana i ka wā e lawe ai i ka lāʻau lapaʻau waha ma ka home
Hoʻomaka ka mālama ʻana ma ka home:
- ʻAʻole pono e hoʻopā ʻia nā lāʻau lapaʻau waha me nā lima ʻole. Hiki ke hoʻonāukiuki
- Holoi maikaʻi i nā lima me ke kopa a me ka wai ma hope o ka lawelawe ʻana i nā lāʻau lapaʻau
- E hoʻohana i nā mīkina lima i ka wā e hoʻololi ai i nā lole a i ʻole nā pepa moe i haumia i ka luaʻi a i ʻole ka maʻi maʻi
- E mālama i nā papa e like me ka ʻōlelo a ke kauka lāʻau
- E mālama pono i nā papa mai nā keiki a me nā holoholona
- E lawe i ka lāʻau lapaʻau waha e like me ka mea i kauoha ʻia
- E lawe i ka papa inoa o nā lāʻau lapaʻau o kēia manawa
- E hoʻolālā no ka huakaʻi, hoʻopiha hou, a me nā hopena pule
- Inā pilikia ʻoe i kēlā me kēia manawa, e kelepona i kāu hui mālama ola
- E haʻi aku i nā mea mālama ola ʻē aʻe e pili ana i nā lāʻau anti-cancer waha
- E hoʻihoʻi i nā lāʻau lapaʻau i hoʻohana ʻole ʻia i ka lāʻau lapaʻau no ka mālama palekana
Nā ʻano lāʻau lapaʻau waha
Ua ʻae ʻia ʻo TGA (ʻo ka TGA ka Therapeutic Goods Authority ma Australia) nā lāʻau lapaʻau maʻi maʻi waha he mau lāʻau e pale ai i ka ulu ʻana a hāpai i ka make ʻana o nā pūnaewele lymphoma. Hoʻoikaika kekahi mau lāʻau lapaʻau i ka ʻōnaehana pale o ka mea maʻi e ʻike i nā pūnaewele lymphoma a paipai i ka luku ʻana i kēia mau cell. Aia kekahi mau papa o kēia mau lāʻau i helu ʻia ma lalo nei.
Hoʻohana ʻia ka chemotherapy waha i ka lymphoma
hope paha |
papa |
Pehea ia hana |
Nā ʻano haʻahaʻa |
ʻO nā hopena ʻaoʻao maʻamau |
| Cyclophosphamide | Kemoterapi: Agena alkylating | Hoʻololi kemika i ka DNA e make ai nā pūnaewele ulu | CLL HL Nhl | ʻO ka helu haʻahaʻa Hoʻoponopono Nausea & luaʻi Pau ka maʻi |
| Holapaau | Kemoterapi: ʻO ka mea hoʻopaneʻe Topoisomerase II | Hoʻopilikia i nā enzymes topoisomerase e hoʻomalu i ka hoʻoponopono ʻana i ke ʻano o ka DNA pono no ka hana hou ʻana | CTCL Nhl | Nausea & luaʻi Pau ka maʻi Kōkua 'Oloke |
| ʻO Chlorambucil | Kemoterapi: Agena alkylating | Hoʻololi kemika i ka DNA e make ai nā pūnaewele ulu | CLL FL HL Nhl | ʻO ka helu haʻahaʻa Hoʻoponopono Nausea & luaʻi Kōkua |
Hoʻohana ʻia nā lāʻau lapaʻau waha ʻē aʻe i ka lymphoma
hope paha |
papa |
Pehea ia hana |
Nā ʻano haʻahaʻa |
ʻO nā hopena ʻaoʻao maʻamau |
| Ibrutinib | BTK Kāohi | Kāohi i kahi enzyme i komo i loko o ka hōʻailona hōʻailona cell cell B e pono ai ke ola a me ka ulu ʻana o nā cell lymphoma | CLL Nā MCL | Nā pilikia puʻuwai puʻuwai Nā pilikia pilikia Ke koko kiʻekiʻe · Nā maʻi maʻi |
| ʻO Acalabrutinib | BTK mea pale | Kāohi i kahi enzyme i komo i loko o ka hōʻailona hōʻailona cell cell B e pono ai ke ola a me ka ulu ʻana o nā cell lymphoma | CLL Nā MCL | Heʻeha Kōkua ʻO ka waiwai loaʻa |
| Zanubrutinib | BTK mea pale | Kāohi i kahi enzyme i komo i loko o ka hōʻailona hōʻailona cell cell B e pono ai ke ola a me ka ulu ʻana o nā cell lymphoma | CLL Nā MCL WM | ʻO ka helu haʻahaʻa Hāmeʻa Kōkua |
| ʻO Idelalisib | P13K Kāohi | Kāohi i kahi enzyme i komo i loko o ka hōʻailona hōʻailona cell cell B e pono ai ke ola a me ka ulu ʻana o nā cell lymphoma | CLL FL | ʻO ka maʻi ʻaʻai ʻana i nā pilikia o ke akepaʻa |
| Venetoclax | BCL2 Kāohi | Kuhi ʻia nā protein i ʻike ʻia e pale aku i ka make ʻana o nā cell lymphoma | CLL | 'O Nausea ʻO ka maʻi maʻi pili koko Ka maʻi maʻi |
| Lenalidomide | ʻAiʻa immunomodulatory | ʻAʻole ʻike ʻia ka mīkini pololei. Manaʻo e hoʻololi i ka ʻōnaehana pale. | Hoʻohana ʻia i kekahi mau NHL | ʻO ka ʻili ʻili Nausea Diarrhea |
| ʻO Vorinostat | Kāohi HDAC | Kāohi i nā enzymes HDAC e pono ai no ka hōʻike ʻana i nā genes i loko o ka DNA e pale i ka ulu ʻana a me ka māhele ʻana o ka lymphoma cell | CTCL | Pau ka maʻi maloo waha ʻO nā maʻi lauoho lauoho |
| Panobinostat | Kāohi HDAC | Kāohi i nā enzymes HDAC e pono ai no ka hōʻike ʻana i nā genes i loko o ka DNA e pale i ka ulu ʻana a me ka māhele ʻana o ka lymphoma cell | HL CTCL | Nā pae magnesium kiʻekiʻe Kiʻekiʻe bilirubin pae Nausea Infections |
| Bexarotene | Retinoids | Hoʻopaʻa koho a hoʻōla i nā mea loaʻa retinoid e hopena i ka hōʻike ʻana o nā genes e hoʻomalu i ka ulu ʻana a me ka hana hou ʻana | CTCL | Paheʻe kaʻili 'O Nausea Haʻahaʻa haʻahaʻa thyroid hormones Infections |
