ʻO nā kumu ulu nā mea kemika hana (hana ʻia e ke kanaka) e paipai ana i nā pūnaewele e puʻunaue a ulu. Nui nā ʻano mea ulu like ʻole e pili ana i nā ʻano cell like ʻole. Hana maoli kou kino i nā mea ulu.
He aha nā mea ulu?
Hoʻokumu ʻia ka Granulocyte-colony stimulating factor (G-CSF) i loko o ke kino e ka ʻōnaehana immune a hoʻoulu i ka hoʻokumu ʻana o hoʻokahi ʻano o ke koko keʻokeʻo keʻokeʻo, ʻo ka neutrophil. Hoʻokomo ʻo Neutrophils i ka hopena inflammatory a nona ke kuleana no ka ʻike ʻana a me ka luku ʻana i nā maʻi maʻi ʻino, nā maʻi maʻi, a me kekahi mau haʻi.
Hiki ke hana ʻia kekahi mau mea ulu ma ka hale hana. Hiki ke hoʻohana ʻia kēia mau mea e hoʻoulu i ka hana ʻana o nā cell hou i nā maʻi e pono ai.
Hiki ke hoʻohana ʻia nā ʻano like ʻole o G-CSF:
- Lenograstim (Granocyte®)
- Filgrastim (Neupogen®)
- Lipegfilgrastim (Lonquex®)
- Pegylated filgrastim (Neulasta®)
ʻO wai ka mea e pono ai nā kumu ulu?
Inā makemake ʻia ka mālama ʻana me G-CSF a i ʻole ma muli o:
- ʻO ke ʻano a me ka pae o ka lymphoma
- ʻO ka chemotherapy
- Inā paha ua loaʻa ka neutropenic sepsis i ka wā ma mua
- Nā lapaʻau i hala
- makahiki
- Ke ola lapaʻau
Nā hōʻailona no G-CSF
Nui nā kumu e pono ai i nā maʻi lymphoma ke loaʻa iā G-CSF. Hiki i nā kumu ke komo:
- Kāohi i ka neutropenic sepsis. ʻO ka Chemotherapy no ka lymphoma ka manaʻo e pepehi i nā pūnaewele lymphoma akā hiki ke hoʻopili ʻia kekahi mau mea ola olakino. Aia kēia me nā keʻokeʻo keʻokeʻo i kapa ʻia he neutrophils. ʻO ka lapaʻau ʻana me G-CSF kōkua i ka helu neutrophil e hoʻōla wikiwiki. Hiki ke hoʻohana ʻia e hōʻemi i ka pilikia o ka neutropenic sepsis. Hiki iā lākou ke pale i ka lohi a i ʻole ka hōʻemi ʻana i ka nui o ka maʻi chemotherapy.
- E mālama i ka neutropenic sepsis. ʻO ka neutropenic sepsis ke loaʻa i ka mea maʻi me ka pae haʻahaʻa o nā neutrophils i kahi maʻi ʻaʻole hiki iā lākou ke hakakā a lilo i septic. Inā ʻaʻole lākou e loaʻa i ka lāʻau lapaʻau koʻikoʻi, hiki ke hoʻoweliweli i ke ola.
- No ka hoʻoikaika ʻana i ka hana ʻana a me ka hoʻoikaika ʻana ma mua o ka hoʻololi ʻana i ka iwi iwi. Hoʻoikaika nā kumu ulu i ka iwi iwi e hana i nā pūnaewele kumu i ka nui. Paipai pū lākou iā lākou e neʻe i waho o ka iwi iwi a i loko o ke kahe koko, kahi e maʻalahi ai ka hōʻiliʻili ʻana.
Pehea ka haawiia?
- Hāʻawi pinepine ʻia ʻo G-CSF ma ke ʻano he injection ma lalo o ka ʻili (subcutaneously)
- Hāʻawi ʻia ka injection mua ma ka haukapila e nānā i nā hopena
- Hiki i ke kahu hānai ke hōʻike i ka mea maʻi a i ʻole ke kanaka kākoʻo pehea e hoʻokomo ai i ka G-CSF ma ka home.
- Hiki i kekahi kahu hānai kaiaulu ke kipa i kēlā me kēia lā e hāʻawi i kahi inikini, a i ʻole hiki ke hāʻawi ʻia ma ke ʻoki GP.
- Hoʻohana pinepine lākou i nā syringes hoʻohana hoʻokahi
- Pono e mālama ʻia nā injections G-CSF i loko o ka friji.
- E lawe i ka injection mai loko mai o ka friji 30 mau minuke ma mua o ka pono. ʻOi aku ka ʻoluʻolu inā he lumi wela.
- Pono nā maʻi e ana i ko lākou mahana i kēlā me kēia lā a makaʻala no nā hōʻailona ʻē aʻe o kahi maʻi.
Nā hopena ʻaoʻao o ka G-CSF injections
E hoʻāʻo mau ʻia nā pae o nā keʻokeʻo keʻokeʻo i loko o ke kino me kahi hoʻāʻo koko ʻoiai e loaʻa ana nā maʻi i nā inikini G-CSF.
Nā hopena ʻaoʻao maʻamau
- 'O Nausea
- ʻO ka wai
- Paena kaona
- kuni
- 'Oloke
- Pau ka lauoho
- ʻO ka maʻi maʻi a i ʻole ka constipation
- Hoʻoponopono
- Hāmeʻa
- Headaches
'Ōlelo Aʻo: hiki i kekahi poʻe maʻi ke loaʻa i ka ʻeha iwi nui, ʻoi loa ma ke kua lalo. Hana ʻia kēia ma muli o ka hoʻopiʻi ʻana o G-CSF i ka piʻi wikiwiki ʻana o nā neutrophils a me ka pane ʻana o ka mumū i ka iwi iwi. Aia ka iwi iwi ma ka pelvic (hip/lalo kua). Hana ʻia kēia i ka wā e hoʻi mai ana ke koko keʻokeʻo. ʻO ka ʻōpio ka mea maʻi ʻoi aku ka nui o ka ʻeha, no ka mea, paʻa mau ka iwi iwi i ka wā ʻōpiopio. ʻO ka mea maʻi maʻi ʻoi aku ka liʻiliʻi o ka ʻiʻo o ka iwi a emi pinepine ka ʻeha akā ʻaʻole i nā manawa a pau. Nā mea e hiki ke kōkua i ka hōʻoluʻolu o ka pilikia:
- ʻO Paracetamol
- Puke wela
- ʻO Loratadine: he antihistamine ma luna o ka counter, e hōʻemi ana i ka pane inflammatory
- E kelepona i ka hui lapaʻau no ka loaʻa ʻana o ka analgesia ikaika inā ʻaʻole kōkua ka mea i luna
E hōʻike i nā hopena koʻikoʻi i kāu hui mālama ola.
Kakaʻikahi ʻaoʻao-hopena
Hiki i kekahi poʻe maʻi ke loaʻa ka spleen nui. E haʻi i ke kauka inā loaʻa iā ʻoe:
- ʻO ka manaʻo o ka piha a i ʻole ka hōʻoluʻolu ma ka ʻaoʻao hema o ka ʻōpū, ma lalo pono o nā iwi ʻaoʻao
- ʻEha ma ka ʻaoʻao hema o ka ʻōpū
- ʻEha ma ka piko o ka poʻohiwi hema
